Thyroid peroxidase antibodies (TPOAb) blood test in Manchester

Get an Thyroid peroxidase antibodies (TPOAb) blood test delivered straight to your door in Manchester. Track what’s going on inside your body and improve your health.

Did you know?

The first ever oral contraceptive was developed at the University of Manchester in 1961.

What is thyroid peroxidase?

Thyroid peroxidase (TPO) is an enzyme that helps convert thyroxine (T4) to triiodothyronine (T3) — these hormones help control your metabolism.

A TPO antibody test checks for the presence of antibodies against TPO. High levels of these antibodies can indicate that you have an autoimmune disorder.

TPOAb is sometimes referred to as anti-thyroid peroxidase antibodies (TPEX).

What is their function?

TPOAb are not normally found in your body. If you have an autoimmune thyroid disorder, these antibodies are produced and attack your thyroid.

Raised TPOAb levels can indicate Hashimoto’s disease (autoimmune thyroiditis) — which causes an underactive thyroid. Up to 95% of people with Hashimoto’s will have TPO antibodies in their blood which makes it a good marker for diagnosing this disease. It's not as common, but they might also indicate Grave’s disease — which causes an overactive thyroid.

What can cause it to change?

Autoimmune thyroid disorders are thought to be caused by a combination of genetic and environmental factors. Risk factors include:

  • a family history of autoimmune diseases
  • being female
  • pregnancy
  • infections
  • iodine intake
  • certain medications
  • stress

What are the most common symptoms?

If your TPOAb levels are rasied, you might have an autoimmune thyroid disorder. This can cause an under or overactive thyroid.

If your thyroid is underactive, like with Hashimoto's disease, common symptoms include:

  • tiredness
  • weight gain
  • depression
  • constipation
  • dry skin
  • brittle hair
  • sensitivity to cold
  • memory problems
  • muscle aches
  • hoarse voice

If your thyroid is overactive, like with Grave's disease, common symptoms include:

  • weight loss
  • increased appetite
  • excessive sweating
  • sensitivity to heat
  • twitching
  • fatigue
  • irritability and anxiety
  • heart palpitations
  • difficulty sleeping

In women, high or low thyroid hormones might affect your period — for example, it might cause heavy or irregular periods.

What can I do to change my levels?

There are a number of nutrients that are important for your thyroid function:

  • Iodine — needed to make thyroid hormones
  • Zinc — needed to make thyroid hormones
  • Selenium — needed to thyroid hormones
  • Iron — plays an important role in thyroid hormone metabolism
  • Vitamin D — plays an important role in your immune function and low levels are linked to autoimmune thyroid disorders

If your levels indicate you have a thyroid disorder, it’s important to work with your doctor to come up with a treatment plan.

What is Thriva?

We’re a subscription-based health tracking company. With our blood testing kits you can take control of your health and see exactly what’s happening inside your body. Learn what lifestyle really works for you and improve everything from your sleep and energy levels to your heart health.

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Get your Thriva kit

Order your test online. We’ll post your kit the next working day via Royal Mail first class delivery.

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Perform your test

Your kit contains everything you need for your simple finger-prick blood test. When you’re done, use the freepost envelope to send it back.

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Results within 48 hours

Your full results, along with a personalised report from a qualified GP, will be available to access online.

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