What is gamma-glutamyl transpeptidase?
Gamma-glutamyl transpeptidase (GGT) is an enzyme found mainly in your liver. A GGT test is used to check for signs of liver damage or disease.
What is its function?
GGT plays a key role in breaking down drugs and toxins.
What can cause it to change?
High GGT levels can be a sign of liver damage or disease.
If you drink too much alcohol, your GGT levels usually increase. Some drugs, including antibiotics and NSAIDs like iburopfen, can also increase your levels.
What are the most common symptoms?
If your GGT levels are high as a result of liver damage, common symptoms include:
- jaundice — yellow skin and eyes
- nausea and vomiting
- unexplained weight loss
- swelling around your eyes, stomach, or legs
What can I do to change them?
To prevent high GGT levels caused by liver damage, avoid too much:
- saturated and trans fats — like fried foods, red meat, cakes, pastries, and cream
- refined carbohydrates — like white bread and white pasta
- added sugars — like fruit juices, fizzy drinks, and sweets
- salt — like frozen foods, salted nuts, and smoked or cured meats
- alcohol — limit to 14 units a week (equivalent to about 6 pints or 7 medium-sized glasses of wine)